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Job Title
Senior Scientist, Computational and Systems Biology

Job Profile
Senior Scientist, Computational and Systems Biology','2809130304','!*!Janssen Research & Development, L.L.C., a Johnson & Johnson company, is recruiting for a Senior Scientist, Computational & Systems Biology (CSB) to be located in Spring House, PA.

Janssen Research & Development, L.L.C. develops treatments that improve the health and lifestyles of people worldwide. Research and development areas encompass novel targets in neurologic disorders, gastroenterology, oncology, infectious disease, diabetes, hematology, metabolic disorders, immunologic disorders, and reproductive medicine.
Thriving on a diverse company culture, celebrating the uniqueness of our employees and committed to inclusion. Proud to be an equal opportunity employer.

Janssen Pharma R&D; seeks scientists with expertise in creatively applying quantitative analysis to pharmaceutical and/or biomedical research. He/she will be part of the Computational & Systems Biology Group (CSB) which is a new, dynamic program that brings together a team of researchers with expertise in mathematics, computer/computational science, physical/natural sciences, and engineering to apply their expertise to areas of biomedical and pharmaceutical research in close collaboration with the other research programs within Janssen. Areas of current focus include computational/systems biology, systems pharmacology, genomic analysis, population genetics, neuroscience, immunology, oncology, cardiovascular and metabolic diseases, infectious diseases, and signal and image processing. Integration and analysis of information across modalities and space/time scales, spanning genomes, cells, circuits and behavior remains an extremely challenging problem, which we expect these researchers to address. We seek senior scientists with strong training and experience in applied quantitative methods and a track record of scholarship. Candidates should possess outstanding communication skills as well as broad biological interests that will enable them to facilitate interactions between laboratory-based researchers throughout Janssen. Previous experience in research within a pharmaceutical environment is a plus. He/She will support therapy areas and other stakeholders from a integrative, systems-level perspective and advance the scientific mission of the business groups. This person will work with other members of the CSB group to plan and execute training programs for scientists and engineers throughout Janssen and enhance the ability of researchers to exploit Informatics in their work. He/she will perform research relevant to the mission of the organization and publish high quality research. This individual will lead computational analysis efforts of high-dimensional datasets from experimental medicine (non-interventional trials) and clinical trials implementing methods and supporting tools for analyzing high-dimensional datasets Identifying novel targets, biomarkers, mechanisms of resistance, and effective therapeutic combinations through the translation of bioinformatics data. He/she will design and implement approaches to solve complex computational and mathematical problems as they relate to interpreting biological data. This includes development of new research directions in the application of Informatics in support of the evolving needs of the R&D; business groups.
','!*!A M.D. and/or Ph.D. in computational sciences, natural sciences, physical sciences, mathematics, medicine or engineering is required
At least 3 years post-graduate experience in the field of bioinformatics, computational/systems biology, drug discovery, computational/statistical genetics or systems pharmacology is required
Candidates with industry experience preferred
Extensive experience analyzing high-dimensional datasets for disease understanding and biomarker discovery is required
Experience with drug discovery and development practices and project support in a large pharmaceutical setting is a plus
Independent, self-motivated and innovative and the ability to excel in a goal-oriented, multifaceted and fast-moving team environment is required
Outstanding communication, organizational and leadership skills, with a successful track record of collaborating with cross-functional scientific teams is required
The role will require up to 25% domestic/international travel
The role will be based in Spring House, PA.

BE VITAL in your career, Be seen for the talent you bring to your work. Explore opportunities within the Johnson & Johnson Family of Companies.

J2W:LI
J2W:BIO
J2W:NSJ
J2W:MZ','North America-United States-Pennsylvania-Spring House','','Janssen Research & Development, LLC. (6084)','','','Informatics','Senior Scientist, Computational and Systems Biology


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Location: USA-PA-Spring House
Posted on
Jul 31,2026
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