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Senior Scientist - Protein Mass Spectrometry - West Chester PA

Company name
Sgs Automotive Services Inc

West Chester, PA

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Job Description:

 Senior Scientist - Protein Mass Spectrometry


 SGS strives to be the testing leader in the pharmaceutical, biopharmaceutical and medical device industries.  Each employee must approach their job as an ongoing commitment to quality testing and customer service in order for the company to succeed.  This means fulfilling commitments in both of the following key result areas:  Our Customers

.  We want to help our customers deliver safe and successful health care products to the public.  We do this by providing responsive, cost-effective testing services that combine outstanding technical quality, top-notch regulatory compliance, and outstanding attention to the specialized needs of our customers.  All SGS staff are expected to make customer service their top priority.  This means that each employee is expected to do whatever is practical to meet our customers’ needs, even if this exceeds the specific responsibilities listed in their job description.

  Our People

.  We consider our people to be our greatest asset, and we provide employees with a work environment that fosters teamwork, growth, flexibility, and innovation.  Our strong commitment to teamwork ultimately translates into long-term trust and reliability for our customers.


PRIMARY RESPONSIBILITIES   Perform analytical studies on biologics utilizing primarily, but not solely, high resolution LCMS in a fast-paced leading Contract Research Organization.

Perform various tasks in support of laboratory operation and maintenance.

 REPORTING LINE  LSS West Chester – General Manager

 SPECIFIC RESPONSIBILITIES Operate and maintain laboratory instrumentation required for cGMP analyses.

Perform/Manage MS qualitative analyses of biologics.  These studies include, but not limited to, protein Molecular weight analysis, peptide mapping, protein sequencing, post-translational modifications qualitative and quantitative analyses, and glycan structural analysis using primarily but not solely high resolution mass spectrometry.

Perform/Manage MS-based quantitative analyses of Proteins and Peptides. These studies include, but not limited to, R&D and cGMP protein quantitation through MRM (e.g. residual proteins, residual Host Cell Proteins), Multiple Attributes Methods, etc… These studies do not include Bioanalytical work.

Prepare chemical solutions and perform detailed and complex analytical procedures (e.g., digestions, purifications, buffer exchanges etc.) following SOP’s and established test Protocols.

Write and review reports, protocols, and any documentation in relation with the performance of the work.

Provide Technical input and support LSS West Chester Customer Service Team whenever required.

Work closely with Quality Assurance to meet all necessary regulatory requirements.

Job requirements

A minimum PhD level scientist with 3-5 years of experience in quantitative and qualitative Protein mass spectrometry or a M.S. level scientist with a minimum of 5 to 7 yrs experience in quantitative and qualitative Protein mass spectrometry.   REQUIRED SKILLS  Have strong hands-on experience with H/UPLC and high resolution mass spectrometry applied to Large Molecules characterization.

Have strong hands-on experience with H/UPLC and high resolution mass spectrometry applied to Large Molecules quantitation.

Experience with de novo protein sequencing (manual and software-assisted data interpretation).

Industry cGMP experience a plus.

Be highly motivated, independent and interactive.

Effectively collaborate with colleagues, both internal and external.

Demonstrate professional verbal and written communication skills.

Be highly organized and capable of multitasking to meet required deadlines.

Have ability to focus on critical tasks, give proper attention to detail.

Company info

Sgs Automotive Services Inc
Website :

Company Profile
SGS provides worldwide, independent services that make a difference in people’s lives. Our international experts help you operate in more efficient and sustainable ways by streamlining processes, improving quality and productivity, reducing risk, verifying compliance and increasing speed to market. Our core service activities cover all industry sectors and touch the products and services that consumers around the world rely on every day. Wherever you are in the world, in whatever industry, you can rely on our international teams of experts to provide you with specialized business solutions to make your business faster, simpler and more efficient. We partner with you to offer independent services that will help you reduce risk, streamline your processes and operate in a more sustainable manner. You can find out more about how we can help you reach your objectives by viewing our corporate video. SGS is the world’s leading inspection, verification, testing and certification company. We are recognized as the global benchmark for quality and integrity. With more than 80,000 employees, we operate a network of more than 1,650 offices and laboratories around the world.

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