Job added in hotlist
Applied job
Contract job
90-day-old-job
part-time-job
Recruiter job
Employer job
Expanded search
Apply online not available
View more jobs in Spring House, PA
View more jobs in Pennsylvania

Job Details

Senior Associate Scientist Immuno Oncology

Company name
Johnson & Johnson Services, Inc.

Location
Spring House, PA

Apply for this job






2 hit(s)  

Profile

Janssen Research & Development, L.L.C., a division of Johnson & Johnson's Family of Companies is recruiting for a Senior Associate Scientist located in Spring House, PA.At the Janssen Pharmaceutical Companies of Johnson & Johnson, what matters most is helping people live full and healthy lives. We focus on treating, curing and preventing some of the most devastating and complex diseases of our time. And we pursue the most promising science, wherever it might be found. Janssen Research & Development, LLC discovers and develops innovative medical solutions to address important unmet medical needs in oncology, immunology, neuroscience, infectious diseases and vaccines, and cardiovascular and metabolic diseases. Please visit http:\/\/www.JanssenRnD.com for more information. We are Janssen. Our mission drives us. Our patients inspire us. We collaborate with the world for the health of everyone in it.Thriving on a diverse company culture, celebrating the uniqueness of our employees and committed to inclusion. Proud to be an equal opportunity employer.As a Senior Associate Scientist within Immuno-Oncology, Oncology Discovery responsibilities will include: \u2022Support the identification, validation, and drug development of novel immuno-oncology therapeutics for the treatment of Oncology indications\u2022\tDesign, execute and interpret studies for the identification, validation, and characterization of antigen-specific immune responses including MHC class I and II immune reactive epitopes\u2022\tEstablish immunogenicity assays with proliferation and cytokine endpoint readouts for the characterization of immune responses to both neo and self-antigens\u2022\tDesign, execute and interpret complex in vitro, ex vivo and in vivo experiments to evaluate mechanism of action associated with immune cell function with the aim of advancing the Oncology pipeline. \u2022\tCommunicate scientific results to multidisciplinary teams and project leader. Comfortable working in a highly matrixed environment\u2022\tMaintain detailed and organized experimental records and stay compliant on all relevant internal and external training requirements\u2022\tQuantify immune cell response by Elispot\/flouropspot assays (e.g. IFN\u03b3, TNF\u03b1, IL-2, IL-10)\u2022\tAnalyze, compare, and report the sensitivity, potency and impact on growth rate of molecules of interest agents by standard cytotoxicity assays (e.g. Incucyte, Cell titer-glo, LDH, MTT)\u2022\tQuantitate soluble cytokine and protein levels from serum, tissue homogenate, and tissue culture supernatant by standard ELISA and other platforms (e.g. MSD, Luminex)\u2022\tCulture multiple primary cell types, and cancer cell line simultaneously under aseptic conditions\u2022\tEstablish robust assay readout metrics (EC50\/IC50, max response, response above background) for the comparison and ranking of experimental agents\u2022\tProcess tissue (blood, lymph nodes, tumor, prostate, lung, muscle, spleen, and thymus) to single cell suspension for analysis of immune cell and stromal cells by Flow cytometry\u2022\tStain and characterize immune cell population by multiparameter (8-16 colors) flow cytometry (e.g. Fortessa, Canto, Celesta)Qualifications\u2022\tA minimum of a BS degree is required \u2022\tA minimum of three years\u2019 experience working in an industry or Biotech laboratory environment is required \u2022\tExperience in design and interpretation of cell based assays\/experiments to interrogate questions in Immunology and compound effects on the immune system is preferred \u2022\tSpecific experience utilizing Elispot\/Flourospot to quantify immune cell activation is required\u2022\tExperience culturing multiple primary and cancer cell line simultaneously under aseptic conditions is required\u2022\tExperience with cytokine expression, proliferation, and cytotoxicity assays is required \u2022\tExperience in molecular biology including RNA, DNA and protein analysis is required\u2022\tExperience with in vivo models of tumor biology, and flow cytometry is required.\u2022\tDetail-oriented, with excellent record-keeping skills\u2022\tExcellent communication and collaborative skills are essential including; interfacing with group leaders to ensure that in vitro and in vivo testing requirements and time lines are met\u2022\tDeveloping and presenting summaries of data, writing clear and succinct study reports; and effective interfacing with other cross functional groups.

Company info

Johnson & Johnson Services, Inc.
Website : http://www.jnj.com

Company Profile
Caring for the world, one person at a time... inspires and unites the people of Johnson & Johnson. We embrace research and science - bringing innovative ideas, products and services to advance the health and well-being of people. Employees of the Johnson & Johnson Family of Companies work with partners in health care to touch the lives of over a billion people every day, throughout the world. Johnson & Johnson was founded more than 120 years ago. Since then, we’ve brought the world new ideas and products that have transformed human health and well-being.

Similar Jobs:
Staff Hydrogeologist
Location : Mount Laurel, NJ
in Mount Laurel New Jersey Founded in 1886, American Water is the largest and most geographically diverse publicly traded U.S. water and wastewater utility company. With headquarters in Voorhees, N.J., the company employs 6,800 de...
Senior Scientist, Computational Biology, Oncology Translational Research','2083180522','!*!Janssen Research & Development, L.L.C., a Johnson & Johnson company, is recruiting for a Senior Scientist, Computational Biology, Oncology ...
Statistical Analyst - Acurian (A PPD Company)','147177','!*!The Statistical Analyst will work closely with members of the Sales, Operations and IT departments. The analyst will be responsible for writing and maintaining SAS code, ...
What I liked about the service is that it had such a comprehensive collection of jobs! I was using a number of sites previously and this took up so much time, but in joining EmploymentCrossing, I was able to stop going from site to site and was able to find everything I needed on EmploymentCrossing.
John Elstner - Baltimore, MD
  • All we do is research jobs.
  • Our team of researchers, programmers, and analysts find you jobs from over 1,000 career pages and other sources
  • Our members get more interviews and jobs than people who use "public job boards"
Shoot for the moon. Even if you miss it, you will land among the stars.
ScientistCrossing - #1 Job Aggregation and Private Job-Opening Research Service — The Most Quality Jobs Anywhere
ScientistCrossing is the first job consolidation service in the employment industry to seek to include every job that exists in the world.
Copyright © 2018 ScientistCrossing - All rights reserved. 21