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Scientist II Translational Development

Location
Andover, MA

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The Company:****
Sarepta Therapeutics is seeking a talented and highly motivated candidate to join our team as a Scientist II
. Qualified candidates will have a background in biochemistry, neuromuscular disease and bioanalytical method development. This person will contribute to assay development, validation and clinical sample testing activities to evaluate treatment efficacy in ongoing Sarepta trials. Additional duties include drafting methods, SOPs, protocols and technical reports and coordinating assay development activities with the pre-clinical Assay Development and Research Biology groups. This position will be located at the Sarepta Therapeutics site in Andover, MA.
Primary responsibilities include but are not limited to:
Conduct GCP/GLP clinical study sample analysis, under the direction of the laboratory director. Supervise other laboratory staff performing sample analysis.
Take a lead role in the development and validation of fit-for-purpose bioanalytical methods for one or more clinical stage programs.
Coordinate activities and timelines through close collaboration with the laboratory head and other laboratory staff.
Maintain a working knowledge of technology and research developments in the field of neuromuscular disease and provide input on biomarker development strategy and implementation. Contribute to scientific publications and presentations at scientific meetings.
Maintain compliant laboratory records. Author technical documents, protocols and reports connected to assay development, validation and clinical sample testing.
Education and Skills Requirements:
Ph.D. or equivalent terminal degree in a relevant scientific area with a minimum of 3 years of experience in bioanalytical and/or diagnostic assay development in a GCP/GLP laboratory environment.
Ability to execute sample handling and analysis with strict adherence to laboratory methods and SOPs.
A strong record of demonstrating analytical reasoning and creative problem solving skills, including a strong grounding in statistical analysis methods and software.
A deep understanding of protein purification and characterization, antibody characterization, immunoassays (ELISA, IHC, Western Blot) and neuromuscular disease research.
A working understanding of Sarepta’s position within the rare disease biotechnology field and the analytical methods used to support our product pipeline.
Experience with relevant ligand binding and mass spectrometry platforms.
Excellent technical writing and communication skills; able to articulate complex scientific concepts and accurately describe methods to diverse functional groups and external stakeholders.
Recognized by former peers, colleagues, managers and direct reports for attributes congruent with Sarepta Values: Drive, Excellence, Resilience, Teamwork, Innovation and Compassion.
Candidates must be authorized to work in the U.S.
Sarepta Therapeutics offers a competitive compensation and benefit package.
Sarepta Therapeutics is an Equal Opportunity/Affirmative Action employer and participates in e-Verify.
Job Location
Andover, Massachusetts, United States

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